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In leukemia, there is an uncontrolled division of certain white blood cells. The cause is a series of changes in the genetic material (DNA) of the bone marrow cells, which produce these abnormal cells. These malignant bone marrow cells also no longer respond to signals to inhibit the production, when enough cells are produced. There are not only different, but far too many cells in the bloodstream. The proliferation of these abnormal cells, the production of normal blood cells is compromised.
Initially there is only an excess of abnormal bone marrow cells. Over time those cells are in the bloodstream and thus into the right bodies. Certain tissues can then filling up with abnormal cells. That is more to brands enlarged lymph nodes, an enlarged spleen and / or an enlarged liver.

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